The BAG1 gene encodes three different isoforms; a predominantly cytosolic form of ~36kD (BAG1S), a ~46kD cytosolic and nuclear form (BAG1M), and a predominantly nuclear form of ~50kD (BAG1L).
BAG1 displays potent neuroprotective activity in vivo against stroke, and could be used for reducing brain injury during cerebral ischemia and neurodegenerative diseases.
BAG1 may also promote chemoresistance, growth factor independence, and anchorage independent cell growth in tumor cells.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/ml, detects a band of ~35kD in PC-3 cell lysate
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid, 0.02% sodium azide.
Specificity：Recognizes human BAG1, NT. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to 14aa near the N-terminus of human BAG1.
