84-1118-85　Synaptic adhesion-like molecule 2 (SALM2, LRFN1, leucine rich repeat and fibronectin type III domain containing 1, KIAA1484, Leucine-rich repeat and fibronectin type III domain-containing protein 1) 100ug　S9111-04

特徴

• Synaptic adhesion-like molecule 2 (SALM2; also leucine-rich repeat and fibronectin type-III domain-containing protein 1 (Lrfn1) is a 105kD member of the Lrfn family of type I transmembrane glycoproteins.
• Human SALM2 is synthesized as a 771aa precursor that contains a 31aa signal sequence, a 505aa extracellular domain, a 21aa transmembrane region, and a 214aa cytoplasmic region.
• The ECD consists of seven leucine-rich repeats, an IgC2-like domain, and a fibronectin type-III domain, tandemly aligned in that order.
• In addition, there are two potential sites for N-linked glycosylation.
• The C-terminal region contains an intracellular PDZ binding domain, which is conserved among SALMs 1-3, but is absent in SALMs 4 and 5.
• Mature human SALM2 shares 96% and 95% sequence identity with mature mouse and rat SALM2, respectively.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.5-1ug/mlWestern Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C for short-term only.
• Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.