84-1117-99 COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2) 100ug C7904-80Q
特徴
- COX2 (Cyclooxygenase 2) is an inducible enzyme.
- It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression.
- Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation.
- COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene.
- In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.
- Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:rabbit
- Source Antibody:human
- Grade:Purified
- Purity:Purified.
- Form:Supplied as a liquid in 0.05M sodium phosphate, 0.1M sodium chloride, 1mM EDTA.
- Specificity:Recognizes human COX 2. Does not cross-react with COX-1. Species Crossreactivity: mouse and rat.
- Isotype:IgG
- Calc Applications Abbrev:E IHC WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to a distinct C-terminal region of human COX-2.
- Shelf Life:1year
- Swiss Prot Number:P35354
- EU Commodity Code:30021010
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