This protein is a member of the regulator of G protein signaling (RGS) family.
RGS family members share similarity with S.
cerevisiae SST2 and C.
elegans egl-10 proteins, which contain a characteristic conserved RGS domain.
RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling.
RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation.
The biological function of this gene, however, is unknown.
Two transcript variants encoding the same isoform exist.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32000Western Blot: 0.5-1.5ug/mlOptimal dilutions to be determined by the researcher.