Epstein-Barr virus-induced gene protein 3 (EBI3), also known as Interleukin-27 beta chain (IL27B) is a widely expressed homolog to the interleukin IL-12p40 subunit protein.
It forms a heterodimer with either IL-12p35 or an IL-12p35 homologue, IL27-p28 (also called IL-28), to create a new cytokine (IL-27).
IL-27 plays an important function in regulating the activity of B and T lymphocytes.
It drives rapid clonal expansion of naive CD4(+) T-cells and strongly synergizes with IL-12 to trigger IFN-gamma production of naive CD4(+) T-cells.
The human Ebi3 encodes a secreted glycoprotein that is expressed in the spleen and tonsils, and at high levels in full-term placenta.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:32000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human EBI3.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide with sequence C-IRYKRQGAARFHR, from the internal region of human EBI3 (NP_005746.2).
