PSCA (Prostate Stem Cell antigen) is a cell surface antigen which is overexpressed in ~40% of primary prostate cancers and in nearly 100% of metastatic ones.
PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas.
Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical xenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human PSA.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide with sequence KAQVSNEDCLQVEN, from the internal region of human PSA (NP_005663.1).
