This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily.
This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues.
Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.
Studies in yeast suggest that the encoded protein is involved in aging.
This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:64000Western Blot: 1-3ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Human Brain (Cerebellum, Cerebral Cortex and Frontal Cortex) lysates
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes both reported isoforms (NP_067090.1 and NP_937850.1) of human Lass1 at ~37kD. Species sequence homology: mouse, rat, bovine.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide with sequence C-KDLREYDTAEAQ, from the internal region of human Lass1.