CCR10 (C-C chemokine receptor type 10), otherwise known as GPR2, (G-protein coupled receptor 2), is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, expressed by melanocytes, dermal fibroblasts, and dermal microvascular endothelial cells, which acts as a receptor for the skin-associated chemokine CCL27 (SCYA27/CTACK), and is implicated in T cell-mediated skin inflammation and possibly skin homeostasis.
Applications:Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistochemistry (paraffin).
Other applications not tested.
Recommended Dilution:Flow Cytometry: 1:25Immunohistochemistry (paraffin): 1:250ELISA: 1:75000Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Positive Control:Spleen or tonsil.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 10mM KHPO4, 140mM sodium chloride, pH7.2, 0.09% sodium azide, 0.1% BSA.
Specificity：Recognizes human CCR10 (C-C chemokine receptor type 10)
Isotype：IgG
Calc Applications Abbrev：E FC IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide VSWGHYSGDEEDAYSAEPLPELC corresponding to aa9-31 of human CCR10.
