CCR8 (C-C chemokine receptor type 8) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts a high-affinity receptor for the chemokine I-309 (CCL1), implicated in the regulation of monocyte chemotaxis and thymocyte apoptosis.
CCR8 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100,000Western Blot: 1:1000Immunohistochemistry (paraffin): 1:400Optimal dilutions to be determined by the researcher.
Positive Control:Spleen
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes mouse CCR8.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to aa7-33 of mouse CCR8.
