The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair.
The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself.
This protein has been shown to phosphorylate period, a circadian rhythm protein.
Two transcript variants encoding the same protein have been found for this gene.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:ELISA: 1:32,000Western Blot: 0.3-1ug/mlOptimal dilutions to be determined by the researcher
Positive Control:Lysates of cell line HEK293
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human CSNK1E at ~45kD.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to C-PASQTSVPFDHLGK from the C-terminal of human CSNK1E. Species sequence homology: mouse, rat, canine.