84-1114-41　Slitrk6 (SLIT and NTRK-like family 6, FLJ22774, FLJ22774, MGC119595, MGC119596, MGC119597, SLIT and NTRK-like protein 6 precursor) 100ug　S1014-18V1

特徴

• SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein.
• These proteins are also homologous to trk neurotrophin receptors in their intracellular domains (1).
• Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2).
• Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas (3).
• Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.5–1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.