84-1113-95　FEZ2, IN (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK cell-associated protein 3Cl, Zygin-2, Zygin II) 100ug　F3965-07

特徴

• Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C.
• elegans UNC-76 (1,2).
• In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues.
• FEZ2 interacts with protein kinase C (PKC)-ζ substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-ζ, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-ζ in a tissue non-specific manner (1).
• FEZ2 can interact with FEZ1 through its c- terminal regions and especially its coiled-coil region (5).
• At least two isoforms of FEZ2 are known to exist.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.5–1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.