84-1113-74　ARG1 (Arginase 1, AI type I arginase, arginase 1 liver) 100ug　A3340-14C

特徴

• Arginase catalyzes the hydrolysis of arginine to ornithine and urea.
• At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function.
• The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle.
• Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Peptide ELISA: 1:2000Western Blot: 0.03-0.1ug/ml.
• Detected a band at ~35kD in human liver lysates.
• Additional bands of unknown identity were also observed at 19-22kD.
• These bands were successfully blocked by incubation with the immunizing peptide
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.