84-1113-30　［取扱停止］AKAP10 (A Kinase (PRKA) Anchor Protein 10, D-AKAP2, MGC9414, PRKA10, A-kinase Anchor Protein 10, Dual-specificity A-kinase Anchoring Protein 2, Mitochondrial A Kinase PPKA Anchor Protein 10, Protein Kinase A Anchoring Protein 10) 100ug　A1102-83E

特徴

• The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.
• This gene encodes a member of the AKAP family.
• The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP.
• This protein is highly enriched in mitochondria.
• It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain.
• The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:64,000Western Blot: 0.3-1μg/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.