84-1113-07　PERP (p53 Apoptosis Effector Related to PMP22, p53 Apoptosis Effector Related to PMP-22, Keratinocytes Associated Protein 1, KCP1, KCP-1, KRTCAP1, P53-induced Protein PIGPC1, PERP TP53 Apoptosis Effector, PIGPC1, THW, TP53 Apoptosis Effector, Transmembrane Protein THW) 50ug　P3353-01F

特徴

• The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.
• PERP (TP53 Apoptosis Effector) is a plasma membrane protein.
• p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis.
• The expression of PERP causes cell death.
• PERP is a mediator of p53 induced apoptosis.
• PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: ParaffinOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.