84-1112-52　Taxilin, alpha (TXLNA, DKFZp451J0118, IL14, MGC118870, MGC118871, RP4-622L5.4, TXLN) 100ug　T1068-75

特徴

• Alpha-Taxilin (TXLN-alpha; also p75 [in rat] and IL-14 alpha) is the founding member of the taxilin family of proteins.
• Although its predicted MW is 62kD, it runs anomalously at 74-76kD in SDS-PAGE.
• Alpha-Taxilin is ubiquitously expressed and participates in intracellular vesicle trafficking.
• In particular, alpha-Taxilin interacts with syntaxin family members that localize to the plasma membrane, providing for SNARE complex formation.
• alpha-Taxilin also regulates the placement of growing protein chains.
• Human alpha-Taxilin is 546aa in length.
• Its defining characteristic is a large coiled-coil region between aa186-491.
• When an alternate start site at Met176 is used, a secreted cytokine is generated termed IL-14 alpha.
• Over aa1-162, human alpha-Taxilin shares 81% aa identity with mouse alpha-Taxilin.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.5-1.0ug/mlWestern Blot: 1.0ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
• Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.