84-1112-48　Syntaxin 16 (STX16, hsyn16, MGC90328, Syn16, SYN16) 100ug　S9205-50

特徴

• Syntaxin 16 (STX16; also SNY16) is a 39kD member of the syntaxin family of proteins.
• It is ubiquitously expressed, embedded in the Golgi membrane, and participates in the fusion of early endosomes with the Golgi stacks.
• Syntaxin 16 contributes one of four coiled-coil domains necessary for retrograde transport.
• Human Syntaxin 16 is a type IV single-pass transmembrane protein (very short lumenal C-terminus) that is 325aa in length.
• It contains a cytoplasmic syntaxin region (aa74-180), a coiled-coil region (aa230-292), and a short, three amino acid C-terminal lumenal sequence.
• There are multiple potential isoforms.
• Two show alternate start sites at Met187 and Met54, while three others show deletions of aa45-48, 28-48 and 28-44, respectively.
• A cytoplasmic form shows an Ala substitution for aa 132-325.
• Over aa165-301, human Syntaxin 16 shares 95% aa identity with mouse Syntaxin 16.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.5-1.0ug/mlWestern Blot: 1.0ug/ml Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile 40-50% glycerol, PBS..
• Aliquot and store at -20°C.
• Reconstituted product is stable for 6 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.