SRCRB4D (Scavenger receptor cysteine-rich domain group B four B-type domain containing) is a 56 kD (predicted), secreted member of the SRCR superfamily.
It is widely expressed and likely plays some role in innate immunity.
Mature human SRCRB4D is 528aa in length.
It contains four SRCR domains (aa58-573), each of which possesses three intradomain disulfide bonds.
Although it contains no potential N-linked glycosylation sites, other types of posttranslational modification cannot be ruled out.
There are three potential isoform variants.
One shows a three aa substitution for aa 271-575, a second shows an 11aa substitution for aa 1-24, and a third shows a 25aa substitution for aa1-416, accompanied by a six aa insertion after Gly445.
Over aa 45-575, human and mouse SRCRB4D share 90% aa identity.
Applications:Suitable for use in Direct ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1.0ug/ml HepG2 human hepatocellular carinoma cell line
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：sheep
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
Specificity：Recognizes human SRCRB4D.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ala45-Ser575 from human SRCRB4D, expressed in CHO cells.
