Syntabulin (also Golgi-localized synaphilin-related protein) is a 75kD molecule that belongs to the syntaxin-binding and kinesin-1 family of motor adaptor proteins.
It is highly spliced, with various forms associated with different tissues.
In neurons, it anchors syntaxin-1 to KIF5B, creating a complex by which synaptic components can be transported to synaptic terminals.
Human Syntabulin is a type II transmembrane (TM) protein 663aa in length.
It contains one coiled-coil region (aa271-353) and a TM domain between aa 606-626.
Alternate splice forms show alternate start sites at Met120 and Met207, a five aa substitution for aa1-8, a 16aa insertion after Lys8, and an eight aa substitution for aa1-76.
Over aa486-653, human Syntabulin shares 83% aa identity with mouse Syntabulin.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 0.5-1.0ug/mlWestern Blot: 1.0ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
Specificity：Recognizes human Syntabulin.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Recombinant human Syntabulin, aa489-656 (E. coli).
