CRF21 (Cytochrome c-releasing factor 21; also C7orf24 or LOC79017) is a 21kD AIG2-like family member.
It is a cytosolic protein that induces the release of Cytochrome c from mitochondria, possibly initiating apoptosis.
Human CRF21 is 188aa in length and is a complex of beta-sheets and alpha-helices that create two terminal domains.
It has been proposed that CRF21 forms homodimers.
There are at least two possible splice variants of human CRF21, one showing a 70aa substitution, while the second variant shows an 18aa substitution for aa97-188.
Full-length human CRF21 is 82% aa identical to mouse CRF21.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1.0ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：sheep
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 0.2 um filtered solution in PBS with 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
Specificity：Recognizes human CRF21 at ~21kD.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Recombinant human Cytochrome c-releasing factor 21, aa1-188 (E.coli).
