84-1111-77　Contactin-3 (CNTN3,(plasmacytoma associated) BIG-1, Brain-derived immunoglobulin superfamily protein 1, Contactin-3, KIAA1496, PANG, PCS, Plasmacytoma-associated neuronal glycoprotein) 100ug　C7865-23

特徴

• Contactin-3 (also BIG-1 in rat and PANG in mouse) is a 150kD member of the TAG/F3 subgroup, contactin family, Ig superfamily hierarchy.
• It is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells.
• Its exact function is unclear, but it likely mediates cell-cell interaction and may promote neurite outgrowth.
• Human Contactin-3 preproprecursor is 1028aa in length.
• It contains a 19aa signal sequence, a 983aa mature region and a 26aa cleavable C-terminal prosegment.
• The mature region shows six C2- type IG-like domains (aa26-593), followed by four fibronectin type III modules (aa598- 992).
• There is one potential alternate start site at Met128.
• Over aa26-992, human Contactin-3 shares 92% aa identity with mouse Contactin-3.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.5-1.0ug/mlWestern Blot: 1.0ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
• Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.