TrkC is a member of the neurotrophic tyrosine receptor kinase family.
TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
TrkC is the receptor for neurotrophin-3 (NT-3).
 Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position.
Applicatons:Suitable for use in Immunohistochemistry.
Other applications have not been tested.
Recommended Dilutions:Immunohistochemistry: 1:1000 -1:3000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile 40-50% glycerol, ddH2O.
Reconstituted product is stable for 12 months at -20°C.
Aliquot and store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes Tyrosine Kinase Receptor C. Species crossreactivity: human, rat, mouse.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Extracellular domain of glycosylated human TrkC protein produced in CHO cells. Cellular localization: Membrane; single-pass type I membrane protein.
