84-1110-01　［取扱停止］FUSIP1 (FUS-interacting Protein (Serine-arginine Rich) 1, FUS Interacting Serine Arginine Rich Protein 1, 40kD SR-repressor Protein, FUSIP2, NSSR, OTTHUMP00000015774, Serine Arginine Repressor Protein 40kD, SFRS13, Splicing Factor SRp38, SRp38, SRp40, TLS-associated Protein TASR1, TLS-associated Protein TASR2, TLS-associated Protein with Ser-Arg Repeats, TLS-associated Protein with SR Repeats, ...　F9215-50

特徴

• FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing.
• Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins.
• FUSIP1 can influence splice site selection of adenovirus E1A pre-mRNA.
• It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.
• Alternative splicing of this gene results in at least two transcript variants encoding different isoforms.
• This antibody is specific for isoform 3 of FUSIP1.
• Applications:Suitable for use Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.5 mg/ml,Optimal dilutions to be determined by the researcher.
• Positve Control:HepG2 whole cell extracts.
• ~22kDa
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C.
• Aliquots are stable for at least 3 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.