Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e.
common colds).
Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis.
Several types have oncogenic potential though most cause self-limiting febrile illnesses characterised by inflammation of conjunctivae and the respiratory tract.
The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections.
It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods.
Immunogen：Synthetic peptide within residues 70-90 of major coat protein VP3 (AAV 2), residues 270-290 of capsid protein VP1 (AAV 6), and residues 270-290 of capsid AAV 3.
