84-1108-61　Corticotropin Releasing Hormone Receptor 1 (CRHR1, CRF1) 100ug　C7903-79C

特徴

• Corticotropin Releasing Hormone Receptor 1 (CRHR1 or CRF1) is a member of the corticotropin-releasing factor family of G-protein-coupled receptors that also includes CRF2.
• It is abundantly expressed in the CNS with major expression in the cortex, cerebellum, hippocampus, amygdala, olfactory bulb and pituitary.
• In the periphery, the receptors are expressed at low levels in the skin, ovary, testis and adrenal gland. It mediates stress and anxiety including stress related colonic motor activity.
• Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot.
• Other applications not tested.
• Recommended Dilutions:Immunofluorescence: 2ug/mlELISA: 1:32,000Western Blot: 0.05-0.2ug/ml.
• ~60-70kD band observed in human brain (cerebellum) and human colon lysates (MW 47.7kD)
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.