APOL1 is a secreted high density lipoprotein which binds to apolipoprotein A-I.
Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL.
It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells.
This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:8000Western Blot: 1.0-3.0ug/ml, ~45kD band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 44.0kD according to NP_003652.2)Optimal dilutions to be determined by the researcher.
Peptide Blocking:Corresponding peptide is available for Peptide Blocking studies.
See A2299-11C-P.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Immunoaffinity chromatography.
Form：Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human APOL1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-NNNYKILQADQE from within the C-terminal region of human APOL1 (NP_003652.2; NP_663318.1).
