84-1108-18 Ubiquitin Hydrolase L1, CT (PGP9.5, Ubiquitin CT Hydrolase L1, UCH, UCHL1, Ubiquitin thiolesterase, PARK5) 1mg U1005D
特徴
- UCHL1 is a thiol protease that catalyzes the hydrolysis of C-terminal of ubiquityl esters and amides to generate ubiquitin monomer.
- It also binds to free monomer and may prevent its degradation by lysosomes.
- It is expressed in neurons and cells of the diffuse neuroendocrine system and their tumors.
- UCHL1 oxidation has been observed in brains of patiens with Alzheimer's and Parkinson's diseases.
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
- Aliquots are stable for at least 12 months at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size：1mg
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein G affinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.2.
- Specificity：Recognizes human UCHL1
- Isotype：IgG
- Calc Applications Abbrev：E
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide (ASSEDTLLKDAAKVCR) corresponding to aa176-191 of human UCHL1
- Shelf Life：1year
- EU Commodity Code：30021010
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