Synphilin-1 is a cytoplasmatic protein that interacts with Alpha-Synuclein in neurons, and plays an important role in synaptic function, protein degradation and Lewy body formation.
Mutation of this protein has a role in the formation of aggregates and cytotoxicity in Parkinson's desease by defective ubiquitination and /or proteosomal inhibition.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:1mg
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2.
Specificity:Recognizes human Synphilin-1
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide (ASKGKNKAA) corresponding to aa911-919 of human Synphilin-1