L-Myc is a nuclear protein with two molecular forms of 60 and 66kD and it plays a role in the control of cell growth, cell cycle progression, neoplasia, and apoptotic cell death.
It contains a basic helix-loop-helix leucine zipper domain required for dimerization and binds DNA as an heterodimer with Max protein.
Both molecular forms have been detected in some carcinoma cell lines.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:100Western Blot: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:1mg
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2.
Specificity:Recognizes human L-Myc
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa224-235, SQEEASERGPQE of human L-Myc