c-Myc is a transcription factor with apparent molecular weight of 62-67 kD which plays an important role in the control of cell growth, cell cycle progression, neoplasia, and apoptotic cell death.
It contains a basic helix-loop-helix leucine zipper domain required for dimerization and binds DNA as an heterodimer with MAX protein.
c-Myc is overexpressed in different tumors such as colorectal, gastric, gallbladder, hepatic, mammary, pulmonary, prostatic, endocrine, as well as hematopoietic neoplasms.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：1mg
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2.
Specificity：Recognizes human c-Myc
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide (KHKLEQLRNSCA) corresponding to aa428-439 of human c-Myc
