84-1107-37 ［取扱停止］XRCC5 (X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-strand-break Rejoining), X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5, 86kD Subunit of Ku Antigen, ATP Dependent DNA Helicase 2 Subunit 2, ATP-dependent DNA Helicase II, ATP-dependent DNA Helicase II 80kD Subunit, ATP-dependent DNA Helicase II 86kD Subunit, CTC Box Binding Factor 85k ... X9505-04
84-1107-37 ［取扱停止］XRCC5 (X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-strand-break Rejoining), X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5, 86kD Subunit of Ku Antigen, ATP Dependent DNA Helicase 2 Subunit 2, ATP-dependent DNA Helicase II, ATP-dependent DNA Helicase II 80kD Subunit, ATP-dependent DNA Helicase II 86kD Subunit, CTC Box Binding Factor 85k ... X9505-04
Telomere length maintenance, an activity essential for chromosome stability and genome integrity, is regulated by telomerase- and telomere-associated factors.
The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance.
The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks.
The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C.
Aliquots are stable for at least 3 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified
Form：As reported
Specificity：Reacts with residues 323-338 [FSKVDEEQMKYKSEGK] of the 80kD Ku80 protein. Sequence is 100% conserved between human, mouse, rat and hamster. Species Crossreactivity: This antibody reacts with human, hamster, rat and mouse.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hm Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues 323-338 [FSKVDEEQMKYKSEGK] of the 80kD Ku80 protein.
Shelf Life：1year
EU Commodity Code：30021010
商品名：XRCC5 (X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-strand-break Rejoining), X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5, 86kD Subunit of Ku Antigen, ATP Dependent DNA Helicase 2 Subunit 2, ATP-dependent DNA Helicase II, ATP-dependent DNA Helicase II 80kD Subunit, ATP-dependent DNA Helicase II 86kD Subunit, CTC Box Binding Factor 85kD, CTC85, CTCBF, DNA Repair Protein XRCC5, Double Strand Break Rejoining, FLJ39089, G22P2, Ku 80, Ku80, Ku Autoantigen 80kDa, Ku 86, Ku86, Ku86 Autoantigen-related Protein 1, KARP1, KARP-1, KUB2, Lupus Ku Autoantigen Protein p86, Nuclear Factor IV, NFIV, Thyroid Lupus Autoantigen, TLAA) 100ug
