Shank is a novel family of post-synaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP.
Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton.
Shank1a is a splice variant of Shank1.
Applications:Suitable for use in GB, Immunofluorescence, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Reacts with residues [SGPIYPGLFDIRSS] of the C-terminus of the Shank1a protein. Species Crossreactivity: Human, rat and mouse. Other species have not been tested.
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Residues [SGPIYPGLFDIRSS] of the C-terminus of the SHANK1 protein.
