84-1105-73 DcR3, NT (TR6, Decoy Receptor 3, TNFRSF6B, TR6, M68) 100ug D1500-25M
特徴
- Decoy Receptor 3 is a 33kD member of the tumor necrosis factor receptor superfamily.
- DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis.
- DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung.
- It may also be found in fetal lung, brain and liver.
- It is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 0.5-1ug/mlImmunohistochemistry (Paraffin): 1ug/ml.
- Requires heat induced epitope retrieval.
- Sodium citrate buffer pH 6.0 is recommended for this purpose
- Optimal dilutions to be determined by the researcher.
- Positive Control:WB: Human heart lysate
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ug
- Host：rabbit
- Source Antibody：human
- Grade：Highly Purified
- Purity：Purified by Ion Exchange chromatography.
- Form：Supplied as a liquid in PBS, 0.02% sodium azide.
- Specificity：Recognizes the N-terminus of human DcR3 at ~33kD. Species Crossreactivity: mouse and rat.
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Synthetic peptide corresponding to amino acids near the N-terminus of human DcR3 precursor.
- Shelf Life：1year
- Swiss Prot Number：O95407
- EU Commodity Code：30021010
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