84-1105-72　ASC, CT (TMS1, Target of Methylation-induced Silencing) 100ug　A3598-05H

特徴

• TMS1, also known as apoptosis-associated speck-like protein containing a CARD (ASC).
• It was first identified as a cytosolic soluble protein that forms insoluble aggregates and promotes caspase-mediated apoptosis.
• The proapoptotic activity is mediated predominantly though the activation of caspase 9.
• It may also be a component of the inflammasome, where it associates with caspase 1, CARD8 and NALP2 to activate proinflammatory caspases.
• TMS1 is widely expressed in human tissue
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/ml ~25kD in HL60 cell lysates
• Immunohistochemistry: frozenOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.