84-1105-09 [取扱停止]Prohibitin 40ug P9007-51E
特徴
- Prohibitin is believed to be a negative regulator of cell proliferation and may also act as a tumor suppressor.
- Mutations in prohibitin have been linked to sporadic breast cancer.
- Prohibitin inhibits DNA synthesis and plays a role in proliferation regulation.
- As yet, it is unclear if it is the protein or the mRNA that exhibits these effects.
- Prohibitin may play a role in regulating mitochondrial respiration activity and aging.
- Prohibitin is located at the inner mitochondrial membrane and is widely expressed in various tissues.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 0.05-0.2ug/mlWestern Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized powder may be stored at -20°C.
- Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C.
- Reconstituted product is stable for 12 months at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size:40ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
- Specificity:Recognizes endogenous levels of human prohibitin protein.
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu Mo
- Immunogen: Synthetic peptide (KLH). derived from within residues 50-100 of human prohibitin (Swiss Prot: P35232).
- Shelf Life:1year
- Swiss Prot Number:P35232
- EU Commodity Code:30021010
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