84-1105-08 [取扱停止]Prohibitin 40ug P9007-51D
特徴
- Prohibitin is located in the inner membrane of the mitochondria.
- It is expressed in a variety of tissues.
- Prohibitin inhibits DNA synthesis and plays a role in regulating negative cell proliferation.
- It may also be a tumor suppressor.
- Mutations in prohibitin have been linked to sporadic breast cancer.
- However, it is not yet clear whether it is the protein itself or the associated mRNA that exhibits these effects.
- Prohibitin may also play a role in regulating mitochondrial respiration activity and in aging.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 0.05-0.2ug/mlWestern Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized powder may be stored at -20°C.
- Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C.
- Reconstituted product is stable for 12 months at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size:40ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
- Specificity:Recognizes endogenous levels of human prohibitin protein. Species sequence homology: mouse and rat.
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide within residues 100-150 of human prohibitin protein (Swiss Prot: P35232).
- Shelf Life:1year
- Swiss Prot Number:P35232
- EU Commodity Code:30021010
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