HDAC2 (Histone deacetylase 2) belongs to the histone deacetylase family.
Histone deacetylases are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3, and H4) via the formation of large multiprotein complexes.
Histone deacetylation forms the tagging for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events.
HDAC2 also forms transcriptional repressor complexes by associating with many different proteins, such as YY1, a mammalian zinc-finger transcription factor.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 0.05-0.2ug/mlWestern Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：40ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
Specificity：Recognizes endogenous levels of human HDAC2 protein.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide derived from the carboxyl terminal residues of the human HDAC2 protein (Swiss Prot: Q92769).
