84-1104-69　［取扱停止］G-Protein Coupled Receptor 30 (GPCR30, GPR30, CEPR, Chemoattractant Receptor-like 2, CMKRL2, DRY12, Flow-induced Endothelial G-protein Coupled Receptor 1, FEG-1, GPCR-BR, G-protein Coupled Estrogen Receptor 1, GPER, IL8-related Receptor DRY12, LERGU, LERGU2, Lymphocyte-derived G-protein Coupled Receptor, LYGPR, Membrane Estrogen Receptor, mER, MGC99678) 40ug　G8600-34F

特徴

• GPR30 (G Protein-coupled Receptor 30), also known as G Protein-coupled estrogen Receptor 1 (GPER), is a member of G protein-coupled receptor family.
• It contains seven hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops.
• GPR30 transduces a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins.
• GPR30 is an orphan receptor and localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives.
• Activating GPR30 via estrogen results in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:ELISA: 0.05-0.2ug/mlWestern Blot: 0.5-1ug/mlImmunohistochemistry: 5-10ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.