CXCR2 is a member of the GPCR family (subfamily, chemokine).
It is a receptor for Interleukin 8 (IL8), which is a powerful neutrophil chemotactic factor.
Binding of IL8 with the receptor activates neutrophils.
This response is mediated by a second messenger system in which G-protein activates phosphatidyl inositol-calcium.
This receptor binds to IL8, GRO/MGSA, and NAP2 with a high affinity.
Its expression has been reported to be in a wide variety of tissues.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:ELISA: 0.05-0.2ug/mlWestern Blot: 0.5-2ug/mlImmunohistochemistry (Paraffin): 5-10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：40ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, pH 7.4, 0.02% sodium azide. Reconstitute with 80ul sterile ddH2O.
Specificity：Recognizes human CXCR2 protein.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the N-terminal extracellular domain of human CXCR2, conjugated to KLH.
