84-1104-41 ［取扱停止］Caspase 10 (FLICE2, Mch4) 40ug C2088-44A
特徴
- Caspase 10 belongs to the peptidase C14A family.
- It is involved in the caspase activation cascade and the execution of apoptosis.
- Caspase 10 is recruited to both Fas- and TNFR-1 receptors in a FADD-dependent manner.
- Caspase 10 may participate in the granzyme B apoptotic pathways.
- It cleaves and activates caspase-3, -4, -6, -7, -8, and -9.
- Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) have been described to date.
- These isoforms all have the same prodomain but different mature large and small subdomains.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 0.05-0.2ug/mlWestern Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized powder may be stored at -20°C.
- Stable for 12 months at -20°C.
- Reconstitute by adding sterile 40-50% glycerol, ddH2O.
- Reconstituted product is stable for 12 months at -20ºC.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size：40ug
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a lypholized powder from PBS, pH 7.4, 0.02% sodium azide.
- Specificity：Recognizes full-length human caspase 10 protein.
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide from residues 169-219 of human caspase 10 protein (Swiss Prot: Q92851). (KLH coupled)
- Shelf Life：1year
- Swiss Prot Number：Q92851
- EU Commodity Code：30021010
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- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
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