This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood.
It delivers retinol from the liver stores to the peripheral tissues.
In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli.
A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.3-1ug/ml Detects a band at ~22kD in human liver and skin lysates
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
Specificity：Species Crossreactivity: Human. Other species not tested.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide, C-QKGNDDHWIVDTDYD, representing the internal region of the human protein according to NP_006735.2. Homology: Human, Mouse, Rat, Dog Epitope: QKGNDDHWIVDTDYD
