Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.
Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily.
This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:250-1:500.
Rat brain membranesImmunohistochemistry: Rat brain sections
Optimal dilutions to be determined by the researcher.
Positive Control Antigen (Included):K9005-10P
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 1% BSA, 5% sucrose, 0.025% sodium azide.
Specificity:Recognizes rat Kv2.1.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Rt
Immunogen:Synthetic peptide corresponding to aa837-853, (CY)HML PGGGA HGSTR DQS of rat Kv2.1. Cellular Localization: Intracellular, C-terminus. Species Sequence Homology: Mouse-100%, human and rabbit-15/17.