Telomere maintenance is essential for protection against changes in telomere length, which has been implicated in ageing and certain cancers.
POT1 (protection of telomeres 1), a telomere regulator, is a single-stranded telomeric DNA-binding protein that controls telomerase-mediated telomere elongation.
Cellular Localization: Nuclear
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Tris-glycine and 150mM NaCl
Specificity:This antibody is specific for POT1. Species Crossreactivity: This antibody reacts with human POT1 protein. The immunogen used for this antibody production has 100% homology with human, 95% with monkey, 82% with rat, and 72% with mouse protein.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:A synthetic peptide made to an internal portion of the human POT1 protein sequence (between residues 200-300).