Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.
PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.
Applications:Suitable for use in Immunocytochemistry/Immunofluorescence, Immunohistochemistry, ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:250-1:1500Immunohistochemistry: 1:10-1:500Immunohistochemistry (frozen): 1:10-1:500Immunohistochemistry (paraffin): 1:10-1:500Immunocytochemistry/Immunofluorescence: 1:10-1:500ELISA: 1:100-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human PTCH2. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：E IC IF IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa226-235, GPFASLEGFR, of human PTCH2.
