Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner.
PARP-2 displays automodification properties similar to PARP-1.
These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery.
Cellular Localization:Nucleus
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% Sodium Azide.
Specificity：N-terminus of human PARP 2 Species Crossreactivity: Human. Others not tested.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Residues 43-59 [QRQESKKMPVAGGKANK] of the 62 kDa human PARP-2 protein.
![PARP2 (Poly ADP-Ribose Polymerase 2, Poly (ADP-ribose) Polymerase Family Member 2, PARP-2, ADP Ribosyltransferase Like 2, ADPRT2, ADPRT-2, ADPRTL2, ADPRTL3, hPARP-2, NAD(+) ADP-ribosyltransferase 2, Poly (ADP-ribosyl) Transferase-like 2, pADPRT-2, Poly (ADP-ribose) Polymerase 2, Poly [ADP-ribose] Synthetase 2, Poly(ADP-ribose) Synthetase) 100ul](https://aimg.as-1.co.jp/c/84/1102/78/85133520.jpg)