84-1102-71　Peptide YY (PYY, Peptide Tyrosine Tyrosine) (BSA & Azide Free) 50ug　P3285-11B

特徴

• Neuropeptide Y (NPY), a neuropeptide colocalized and abundantly released with the neurotransmitter norepinephrine in nervous system, synthesized by postnatal olfactory epithelium of sustentacular cells.
• It promotes the proliferation of postnatal neuronal precursor cells and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system.
• NPY a 97aa peptide in mouse, human (chr 7p15.1) and 98aa in rat has a mol.
• wt of 11kD.
• NPY shows sequence homology to Peptide YY (PYY) and over 50% homology in amino acid and nucleotide sequence to Pancreatic Polypeptide (PNP or PPY), all of these homologous peptides has a 36aa mature peptide characterized by a hairpin loop.
• PYY: Secreted as 97aa precursor from endocrine cells in the lower small intestine, colon, and pancreas.
• It acts on the gastrointestinal tract as an inhibitor of gastric acid secretion, gastric emptying, and digestive enzyme secretion by the pancreas, and gut motility.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml.
• See P3285-11A
• Western Blot: 1-10ug/ml using ECL technique
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.