This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases.
It is a component of the mitochondrial network.
Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness.
Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
Specificity：Species Crossreactivity: This antibody reacts with the human protein. It has not been tested against any other species.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Ch Hu Mo Rt
Immunogen：A synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O60313]. Homology: 100% human, mouse, rat, and chicken
