Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation.
It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
SUBUNIT: Monomer.
Interacts with GABRG2, NSF, GOSR1 and beta-tubulin.
Interacts with ULK1.
Cellular Localization:Golgi apparatus.
Tissue Specificity:Ubiquitous.
Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle.
Expressed at very low levels in lung, thymus and small intestine.
Belongs to the MAP1 LC3 family.
Applications:Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material.
Specificity：IHC, WB and ELISA confirmed the specificity for GABARAP L2 . Species Crossreactivity: Human, rat.
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：A synthetic peptide corresponding to the N-terminal of human GABARAP L2 (GABARAPL2) protein has been used as the immunogen. The sequence is homologous with mouse and rat form of GABARAP L2 (GABARAPL2).
