Interferon-induced transmembrane protein 3(Ifitm3); Fragilis Official Gene Symbol: Ifitm3 Gen Bank Accession Number: NM_025378 Gene ID: 66141(Mouse) Gene Map Locus: 7F5 (Mouse) Fragilis is an IFN-induced transmembrane protein that belongs to the highly conserved fragilis protein family.
It consists of an N-terminal signal sequence, 2 putative transmembrane domains, 3 potential phosphorylation sites and C-terminal Leucine-zipper.
It is expressed in early embryos and nascent primordial germ cells and is associated with Germ cell specification and development.
It is cell surface protein and might be important in mediating interactions amongst germ cells and their surrounding neighbors.
It is also suggested that it might be involved in anti-proliferative signaling and homotypic cell adhesion.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Positive Control: NIH 3T3
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Specificity：Recognizes mouse Fragilis. Species sequence homology: rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide from amino acid region 1-50 of mouse Fragilis. Cellular Localization: Cell Membrane
