FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C.
FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes.
The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus.
Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies.
A minimum of 8 FA genes have been identified.
Cellular Localization: The major form is nuclear.
The minor form is cytoplasmic.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Purity：Whole antisera
Form：As reported
Specificity：Species Crossreactivity: This antibody reacts with the human protein.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A C-Terminal peptide within residues 550- 622 of 622. Homology: 100% homology with human protein. 88% homology with mouse protein.
